Michael Castro M.D. – 医学博士

职位:血液学/肿瘤学专家
科室:肿瘤专科
擅长:胰腺癌、肝胆肿瘤等消化系统肿瘤
执业证书编号:144118
美国内科医学委员会——内科学医师资格认证
美国内科医学委员会——内科肿瘤学医师资格认证

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医疗专长

迈克尔·卡斯特罗(Michael Castro)博士,毕业于美国哥伦比亚大学医学院,深耕于肿瘤内科治疗领域二十余年。临床擅长进行癌症的免疫治疗和精准医疗,即使用基因检测和生物标记物,根据不同的肿瘤代谢和易感性,为癌症患者制定更有效、毒性更小的精准治疗方案。卡斯特罗博士可提供全面的肿瘤医疗方案,包括癌症精准医疗、辅助疗法、终末期治疗、姑息疗法、以及癌症预防、遗传性筛查与检测等。他的诊疗范围涵盖多种恶性实体肿瘤,专精于胃癌、结直肠癌、食管癌、胰腺癌、肝胆肿瘤等消化系统实体肿瘤的个性化诊治。

迄今卡斯特罗博士已经撰写并发表了超过30多篇的同行评议文章。自2011年以来,卡斯特罗一直被《美国新闻和世界报道》(US News and World Report)评选为美国顶级医生之一,被美国檀香山杂志评选为夏威夷最顶尖的医生之一(Hawaii’s Top Doctors)。

教育背景

医学院:哥伦比亚大学内科与外科学院(Columbia University College of Physicians & Surgeons),获得医学博士学位;

实习/住院医师训练: St Luke’s-罗斯福医疗中心(St Luke’s-Roosevelt Hospital Center)内科实习和住院医师培训;

专科临床培训:西奈山赫斯科学和医学中心(Mt Sinai SOM)血液学和肿瘤学专科临床培训,;

进阶培训:MD安德森癌症中心(MD Anderson Cancer Center)高剂量白细胞介素2培训。

荣誉与奖项

2015年、2016年,获得由《新闻周刊》(Newsweek)评选的“美国顶尖医生”荣誉称号(Top Doctors in America);
2014-2016年,获得由《檀香山杂志》(Honolulu Magazine)评选的“檀香山顶尖医生“荣誉称号(Top Doctors in Honolulu);
2013年,获得“CMS Stage 1 HER”荣誉;
2011年,获得由《美国新闻与世界报道》(US NEWS AND WORLD REPORT)CASTLE CONNOLLY评选的“美国顶尖医生”荣誉称号(TOP DOCTORS IN AMERICA)

出版物摘选

摘要或海报

Drug efflux pump expression in 50,000 molecularly-profiled cancer patients. Rebecca Feldman, Brian L. Abbott, Sandeep K. Reddy, Michael Castro, J Clin Oncol 33, 2015 (suppl; abstr 11108), 2015 ASCO Annual Meeting, 6/2015

Expression patterns of a taxane sensitivity panel in 25,000 cancer patients. Brian L. Abbott, Rebecca Feldman, Sandeep K. Reddy, Michael Castro, J Clin Oncol 33, 2015 (suppl; abstr e22235), 2015 ASCO Annual Meeting, 6/2015

Potential impact of different methodologies for detecting EGFR mutations in selecting chemotherapy for patients with lung cancer. Ryan P. Bender, Anatole Ghazalpour, Zheng Tan, Zoran Gatalica, Les Paul, Sandeep K. Reddy, Michael Castro, J Clin Oncol 31, 2013 (suppl; abstr e19006), 2013 ASCO Annual Meeting, 6/2013

Biomarker analysis of glioblastoma and potential implications for therapy. Joanne Xiu, Rebecca Anne Feldman-Moreno, David Arguello, Zoran Gatalica, Anatole Ghazalpour, Ryan P. Bender, Michael Castro, Sandeep K. Reddy, Gargi Dan Basu, Les Paul, J Clin Oncol 31, 2013 (suppl; abstr 2041), 2013 ASCO Annual Meeting, 6/2013

Pharmacokinetics of BSI-201, A poly (ADP-ribose) polymerase-1 (PARP1) inhibitor in cerebrospinal fluid of a breast cancer patient with carcinomatous meningitis. M Castro, L Li, TE Stallings., PROC AM SOC CLIN ONCOL 2010, ABSTRACT 48374, ASCO Annual Meeting 2010, 6/2010

Pharmacogenetic correlates of benefit from gemcitabine and platinum in patients with advanced bladder cancer. M CASTRO, A NEUMANN, M KONICHEXKY, K DANNENBERG, S STEMMER, PROC AM SOC CLIN ONCOL 2004 ABSTRACT 3203, ASCO Annual Meeting 2004, 6/1/2004

Successful use of anti-CD20 monoclonal antibody, Rituxan, in patients with non-Hodgkins lymphoma and renal insufficiency CASTRO MP, VANAUKEN J, SPONZO RW., AM SOC CLIN ONCOL 2001, 20:3325., ASCO Annual Meeting 2001, 6/1/2001

Impact of risk stratification on mammographic interpretation. R SPONZO, T ASHIKAGA, C HOWLAND, P CISEK, MP CASTRO, PROC AM SOC CLIN ONCOL 2000, 19:335., ASCO Annual Meeting 2000, 6/1/2000

讲座

Personalized Medicine in Oncology: Recent Updates

其他

TIMING IS EVERYTHING OR COULD BE. M. Castro, J CLIN ONCOL 21: 755, 2003.

http://hwmaint.jco.ascopubs.org/cgi/content/full/21/4/755-a

2003

THE SIMPLETON’S ERROR IN DRUG DEVELOPMENT. M. Castro, J CLIN ONCOL 2002 20: 4606-7.

http://jco.ascopubs.org/content/20/23/4606

杂志论文:

Mismatch repair deficiency associated with complete remission to combination programmed cell death ligand immune therapy in a patient with sporadic urothelial carcinom… Castro MP and Goldstein N, Journal for ImmunoTherapy of Cancer, 12/15/2015

Successful use of next generation genomic sequencing (NGS)-directed therapy of clear cell carcinoma of the ovary (CCCO) with trametinib and metformin in a patient with… Michael P. Castro, Bradford P. Whitcomb, Deborah A. Zajchowski, and Robert L. Coleman, Gynecologic Oncology Research and Practice 2015, 2:4, 8/28/2015

Metastatic Cancer of Cowper’s Gland: A Rare Cancer Managed Successfully by Molecular Profiling. Myers CE, Gatalica Z, Spinelli A, Castro M, Linden E, Sartor O, Sargent M., Case Rep Oncol. 2014 Jan 16;7(1):52-7., 2014

Apocrine carcinoma of the breast: a comprehensive review. Vranic S, Schmitt F, Sapino A, Costa JL, Reddy S, Castro M, Gatalica Z., Histol Histopathol. 2013 Nov;28(11):1393-409. Epub 2013 Jun 17., 6/13/2013

Peripheral sensory neuropathy—fighting cold with cold M. Castro, Lancet Oncology Volume 9, No. 5, p415–416, May 2008, 2008

Pharmacogenetics in the clinic: new questions about tamoxifen M. Castro, J Oncol Prac 2006 2:100, 1/1/2006

Thymidine reduce: an antidote for pemetrexed related toxicity in the setting of acute renal failure Michael Castro, J Clin Oncol 2003, 21:4066, 1/1/2003

Cerebrospinal fluid gastrin releasing peptide in the diagnosis of leptomeningeal metastases from small cell carcinoma Michael P. Castro M.D., Tom J. McDonald M.D., Stephen J. Qualman M.D. andThomas M. Odorisio M.D., Cancer Volume 91, Issue 11, pages 2122–2126, 1 June 2001, 5/31/2001

Acute tumor lysis syndrome associated with concurrent biochemotherapy of metastatic melanoma: a case report and review of the literature M P Castro, J Vanauken P, Spencer-CisekS, LeghaR, W Sponzo, Cancer 1999 Vol 85 (1055-1059), 1999

Efficacy of gemcitabine in the treatment of patients with gallbladder carcinoma: a case report MP Castro, Fodor L, Orlandi L, Cancer 1998 Vol 82 (639-641), 1/1/1998

书籍或图书章节

Heme-Onc Secrets Chapter: Targeted Therapy

Michael Castro

Editors: M. WOOD.UNIVERSITY OF VERMONT PRESS, Burlington2003